MASIC: a software program for fast quantitation and flexible visualization of chromatographic profiles from detected LC-MS(/MS) features.
| Title | MASIC: a software program for fast quantitation and flexible visualization of chromatographic profiles from detected LC-MS(/MS) features. |
| Publication Type | Journal Article |
| Year of Publication | 2008 |
| Authors | Monroe ME, Shaw JL, Daly DS, Adkins JN, Smith RD |
| Journal | Comput Biol Chem |
| Keywords | Algorithms, Chromatography, Liquid, Computer Simulation, Mass Spectrometry, Peptides, Software |
| Abstract | Quantitative analysis of liquid chromatography (LC)-mass spectrometry (MS) and tandem mass spectrometry (MS/MS) data is essential to many proteomics studies. We have developed MASIC(2) to accurately measure peptide abundances and LC elution times in LC-MS/MS analyses. This software program uses an efficient processing algorithm to quickly generate mass specific selected ion chromatograms from a dataset and provides an interactive browser that allows users to examine individual chromatograms with a variety of options. |
| DOI | 10.1016/j.compbiolchem.2008.02.006 |
| PubMed ID | 18440872 |
| PubMed Central ID | PMC2487672 |
| Grant List | AI 489401 / AI / NIAID NIH HHS / United States P41 RR018522-05 / RR / NCRR NIH HHS / United States RR 018522 / RR / NCRR NIH HHS / United States |
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