U.S. Department of Energy

Pacific Northwest National Laboratory

MASIC: a software program for fast quantitation and flexible visualization of chromatographic profiles from detected LC-MS(/MS) features.

TitleMASIC: a software program for fast quantitation and flexible visualization of chromatographic profiles from detected LC-MS(/MS) features.
Publication TypeJournal Article
Year of Publication2008
AuthorsMonroe ME, Shaw JL, Daly DS, Adkins JN, Smith RD
JournalComput Biol Chem
KeywordsAlgorithms, Chromatography, Liquid, Computer Simulation, Mass Spectrometry, Peptides, Software
Abstract

Quantitative analysis of liquid chromatography (LC)-mass spectrometry (MS) and tandem mass spectrometry (MS/MS) data is essential to many proteomics studies. We have developed MASIC(2) to accurately measure peptide abundances and LC elution times in LC-MS/MS analyses. This software program uses an efficient processing algorithm to quickly generate mass specific selected ion chromatograms from a dataset and provides an interactive browser that allows users to examine individual chromatograms with a variety of options.

DOI10.1016/j.compbiolchem.2008.02.006
PubMed ID18440872
PubMed Central IDPMC2487672
Grant ListAI 489401 / AI / NIAID NIH HHS / United States
P41 RR018522-05 / RR / NCRR NIH HHS / United States
RR 018522 / RR / NCRR NIH HHS / United States
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