U.S. Department of Energy

Pacific Northwest National Laboratory

Tao Liu

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Biography:

Tao Liu is a Senior Staff Scientist in the Integrative Omics Group in the Biological Sciences Division at PNNL. His work at PNNL has centered on developing and applying innovative methods and technologies that enable high-throughput, sensitive, and quantitative LC-MS-based proteomics measurements of complex biological and clinical samples. Applications of these technologies include in-depth and robust characterization of proteome and post-translational modifications (PTMs) in tissue and biofluids for cancer biology and biomarker development for cancers and neurologic diseases. He is currently the principle investigator of the National Cancer Institute (NCI) Clinical Proteomic Tumor Analysis Consortium (CPTAC) Proteome Characterization Center, the NCI Early Detection Research Network (EDRN) Biomarker Reference and Resource Center, and the Department of Defense Framingham Projects as part of the Cancer Moonshot efforts at PNNL. Many of these cancer projects integrate global proteomics data with PTM measurements (e.g., phosphorylation, acetylation, O-GlcNAcylation) and other omics data (e.g., genomics, glycomics).

Prior to joining PNNL, Dr. Liu was a postdoc at the Howard Hughes Medical Institute at the University of Washington. He received his B.S. degree in Chemistry from Nanchang University, China, in 1996 and a Ph.D. degree in Biochemistry and Molecular Biology in 2001 from Shanghai Institute of Biochemistry, Chinese Academy of Sciences.

Research Interests:
  • Quantitative proteomics and PTMs
  • Biomarker discovery and verification
  • Integrative omics and cancer biology
  • Neurologic diseases (e.g., chronic fatigue, multiple sclerosis)
Education:
  • Ph.D., Biochemistry and Molecular Biology, Shanghai Institute of Biochemistry, Chinese Academy of Sciences, Shanghai, China, 2001
  • B.S., Chemistry, Nanchang University, Nanchang, China, 1996
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