Unraveling the isomeric heterogeneity of glycans: ion mobility separations in structures for lossless ion manipulations
Title | Unraveling the isomeric heterogeneity of glycans: ion mobility separations in structures for lossless ion manipulations |
Publication Type | Journal Article |
Year of Publication | 2018 |
Authors | Nagy G., Attah I.K, Garimella S.VB, Tang K., Ibrahim Y.M, Baker E.S, Smith R.D |
Journal | Chem. Commun. (Camb.) |
Abstract | To address the challenges associated with glycan analyses, we have implemented a structures for lossless ion manipulations (SLIM) serpentine ultra-long path with extended routing (SUPER) ion mobility-mass spectrometry (i.e. SLIM SUPER IM-MS) platform to achieve much higher resolution of isomeric glycoforms. We have demonstrated the potential of this platform as a future component of the glycomics toolbox. |
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