U.S. Department of Energy

Pacific Northwest National Laboratory

Characterization of ion dynamics in structures for lossless ion manipulations.

TitleCharacterization of ion dynamics in structures for lossless ion manipulations.
Publication TypeJournal Article
Year of Publication2014
AuthorsTolmachev AV, Webb IK, Ibrahim YM, Garimella SVB, Zhang X, Anderson GA, Smith RD
JournalAnal Chem
KeywordsElectricity, Electrodes, Ions, Mass Spectrometry, Radio Waves
Abstract

Structures for Lossless Ion Manipulation (SLIM) represent a novel class of ion optical devices based upon electrodes patterned on planar surfaces, and relying on a combined action of radiofrequency and DC electric fields and specific buffer gas density conditions. Initial experimental studies have demonstrated the feasibility of the SLIM concept. This report offers an in-depth consideration of key ion dynamics properties in such devices based upon ion optics theory and computational modeling. The SLIM devices investigated are formed by two surfaces, each having an array of radiofrequency (RF) "rung" electrodes, bordered by DC "guard" electrodes. Ion motion is confined by the RF effective potential in the direction orthogonal to the boards and limited or controlled in the transversal direction by the guard DC potentials. Ions can be efficiently trapped and stored in SLIM devices where the confinement of ions can be "soft" in regard to the extent of collisional activation, similarly to RF-only multipole ion guides and traps. The segmentation of the RF rung electrodes and guards along the axis makes it possible to apply static or transient electric field profiles to stimulate ion transfer within a SLIM. In the case of a linear DC gradient applied to RF rungs and guards, a virtually uniform electric field can be created along the axis of the device, enabling high quality ion mobility separations.

DOI10.1021/ac502054p
Alternate JournalAnal. Chem.
PubMed ID25152178
PubMed Central IDPMC4175726
Grant ListP41 GM103493 / GM / NIGMS NIH HHS / United States
P41 GM103493-11 / GM / NIGMS NIH HHS / United States
Area of Research: 
| Pacific Northwest National Laboratory