U.S. Department of Energy

Pacific Northwest National Laboratory

Data Extraction and Analysis for LC-MS Based Proteomics (2007)

This short course at US HUPO discussed the use of two different LC-MS data extraction and analysis platforms to demonstrate how high mass measurement accuracy mass spectrometry and high resolution liquid chromatography can be used for higher-throughput proteomics. The topics discussed included:

  • LC-MS feature extraction
  • Experimental design and analysis of large LC-MS datasets
  • Identification and characterization of peptides and proteins using LC-MS.

These topics were aimed at getting increasing information content from LC-MS experiments both within customized and commercially available LC-MS systems.

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