U.S. Department of Energy

Pacific Northwest National Laboratory

Post Doctorate RA - Quantitative Proteomics

Job Description

This postdoctoral position on quantitative proteomics focuses on the development of and application of targeted protein quantification techniques for studying specific cellular pathways at the molecular level and for verification of protein candidate biomarkers for diagnosis, prognosis, and therapeutics from cells, tissues, and biofluids.  The preferred candidate would have a Ph.D. degree in either analytical chemistry or biochemistry.  Although not required, hands-on experience in mass spectrometry, proteomics, LC separations, posttranslational modifications, and data analysis will be considered as a plus.  Efforts will include methods development, sample preparation and separation methods for enhancing reproducibility and sensitivity, and applications of specific candidate verifications in different sample types.  Potential projects include the evaluation of organ transplant stability, verification of biomarkers for a variety of cancers, and signal transduction pathways in disease.  The successful candidate will be expected to work effectively with an interdisciplinary team of researchers, be self-motivated, and have excellent verbal and written communication skills.  The successful candidate will assist, and possibly lead, in the preparation and presentation of papers, posters, reports, etc. Additionally, he/she will use project management systems at PNNL, maintain an accurate laboratory notebook, adhere to Environmental Safety and Health (ES&H) Operations, and follow security requirements as well as directorate/group policies.
This is a full-time, limited term employment position. The duration of this appointment is two years, with the option of extending the appointment for up to three years, depending on project funding and individual performance. 

Minimum Requirements

Candidates must have received a PhD within the past five years from an accredited college or university.  All staff at the Pacific Northwest National Laboratory must be able to demonstrate the legal right to work in the United States.


Strong organization and communication skills are needed to work efficiently in a team environment. Background in Biochemistry, Chemistry, or Biology is required.  

Equal Employment Opportunity

Pacific Northwest National Laboratory (PNNL) is an Affirmative Action / Equal Opportunity Employer and supports diversity in the workplace.  All employment decisions are made without regard to race, color, religion, sex, national origin, age, disability, veteran status, marital or family status, sexual orientation, gender identity, or genetic information.  All staff at the Pacific Northwest National Laboratory must be able to demonstrate the legal right to work in the United States.

Job ID: 303226

Directorate: Fundamental & Computational Sciences

Group: Omic Training Coordination


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